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Anim Biosci > Volume 35(8); 2022 > Article
Review Paper
Animal Bioscience 2022;35(8): 1109-1120.
https://doi.org/10.5713/ab.21.0485    Published online January 21, 2022.
An updated review on probiotics as an alternative of antibiotics in poultry — A review
Muhammad Umar Yaqoob1  , Geng Wang1  , Minqi Wang1,* 
College of Animal Science, Zhejiang University, Key Laboratory of Animal Nutrition and Feed Science (Eastern China), Ministry of Agriculture, Hangzhou 310058, China
Correspondence:  Minqi Wang, Tel: +86-571-88982112, Fax: +86-571-88982650, Email: wangmq@zju.edu.cn
Received: 28 October 2021   • Revised: 21 December 2021   • Accepted: 18 January 2022
Antibiotics used to be supplemented to animal feeds as growth promoter and as an effective strategy to reduce the burden of pathogenic bacteria present in the gastro-intestinal tract. However, in-feed antibiotics also kill bacteria that may be beneficial to the animal. Secondly, unrestricted use of antibiotics enhanced the antibiotic resistance in pathogenic bacteria. To overcome above problems, scientists are taking a great deal of measures to develop alternatives of antibiotics. There is convincing evidence that probiotics could replace in-feed antibiotics in poultry production. Because they have beneficial effects on growth performance, meat quality, bone health and eggshell quality in poultry. Better immune responses, healthier intestinal microflora and morphology which help the birds to resist against disease attack were also identified with the supplementation of probiotics. Probiotics establish cross-feeding between different bacterial strains of gut ecosystem and reduce the blood cholesterol level via bile salt hydrolase activity. The action mode of probiotics was also updated according to recently published literatures, i.e antimicrobial substances generation or toxin reduction. This comprehensive review of probiotics is aimed to highlight the beneficial effects of probiotics as a potential alternative strategy to replace the antibiotics in poultry.
Keywords: Growth; Immunity; Intestinal Health; Poultry

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