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https://doi.org/10.5713/ab.21.0302    [Accepted] Published online October 21, 2021.
Disinfection of various materials with 3-(trimethoxysilyl)-propyldimethyloctadecyl am-monium chloride in hatchery facilities
Yu-Jin Kim1  , Jun-Beom Kim2  , Chang-Seon Song1,2,*  , Sang-Soep Nahm1,* 
1College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea
2KCAV Co., Ltd., Seoul 05029, Korea
Correspondence:  Chang-Seon Song,Email: songcs@konkuk.ac.kr
Sang-Soep Nahm,Email: songcs@konkuk.ac.kr
Received: 29 June 2021   • Revised: 28 July 2021   • Accepted: 29 June 2021
Surface disinfection is important in the proper running of livestock farms. Howev-er, disinfection of farm equipment and facilities is difficult because they are made of different materials, besides having large surface areas and complex structures. 3-(trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride (Si-QAC) is a quaternary ammonium salt-based disinfectant that attaches to various surfaces by forming covalent bonds and maintains its disinfecting capacity for a considerable time. Our aim was to evaluate the potential use of Si-QAC for disinfection of farm equipment and facilities.
The short- and long-term antimicrobial and antiviral effects of Si-QAC were evalu-ated in both laboratory and farm settings using modified quantitative assessment method based on the standard operating procedures of the United States Environmental Protection Agency.
Si-QAC was highly effective in controlling the growth of the Newcastle disease vi-rus and avian pathogenic Escherichia coli. Electron microscopy revealed that the mechanism underlying the disinfection activity of Si-QAC was associated with its ability to damage the outer membrane of the pathogen cells. In the field test, Si-QAC effectively reduced viral contamination of surfaces of equipment and space.


Our results suggest that Si-QAC has great potential as an effective chemical for disinfecting farm equipment and facilities. This disinfectant could retain its disinfection ability longer than other commercial disinfectants that could expect to contribute to better farm bi-osecurity.
Keywords: Biosecurity; Disinfection; FE-SEM; Hatchery; Long-lasting Disinfectant; Si-QAC
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