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Review Paper
Asian-Australasian Journal of Animal Sciences 2000;13(2): 236-243.
https://doi.org/10.5713/ajas.2000.236    Published online February 1, 2000.
The Manipulation of Milk Secretion in Lactating Dairy Cows - Review -
M. T. Rose, Y. Obara
A number of developments have occurred over recent years that are being used commercially or have the potential to increase the milk yield and consequently the efficiency of dairy cows. Bovine growth hormone is the most widely known of several attempts that have been made to alter the metabolic endocrinology of dairy cows to increase the rate of milk secretion. The factors affecting the milk yield response to growth hormone, growth hormone-releasing factor, thyroxine and placental lactogen as well as to the immuno-neutralization of somatostatin are briefly considered. Secondly, the recent greater understanding of the mechanism by which the milk yield is increased following more frequent milking, which has resulted from the identification and characterization of the feedback inhibitor of lactation (FIL) protein, is reviewed. The identification of this protein provides new avenues of research which may lead to a reduction in the rate of decline in milk yield with advancing lactation or to undiminished milk yields despite a reduction in frequency with which the animals are milked.
Keywords: Milk Secretion; Growth Hormone; Immuno-Neutralization; Feedback; Inhibitor of Lactation; Review

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