Matrix family1) | Detailed matrix information | Start position2) | End position2) | Matrix similarity3) |
---|---|---|---|---|
V$ZF08 | KRAB-zinc finger protein synten (KID3) | 2 | 12 | 0.941 |
V$ZFHX | AREB6 (Atp1a1 regulatory element binding factor 6) | 20 | 32 | 0.974 |
V$IRFF | Interferon regulatory factor 4 | 19 | 43 | 0.936 |
V$IKRS | Ikaros 2, potential regulator of lymphocyte differentiation | 33 | 45 | 0.921 |
V$MIZ1 | Myc-interacting Zn finger protein 1, zinc finger and BTB domain containing 17 (ZBTB17) | 40 | 50 | 0.975 |
V$NKXH | Homeodomain factor Nkx-2.5/Csx | 40 | 58 | 0.919 |
O$INRE | Drosophila initiator motifs | 49 | 59 | 0.906 |
V$NKXH | Homeodomain protein NKX3.2 (BAPX1, NKX3B, Bagpipe homolog) | 46 | 64 | 0.948 |
V$KLFS | Krueppel-like factor 12 (AP-2rep) | 47 | 65 | 0.922 |
V$MOKF | Ribonucleoprotein associated zinc finger protein MOK-2 (human) | 57 | 77 | 0.97 |
V$WHNF | Winged helix protein, involved in hair keratinization and thymus epithelium differentiation | 66 | 76 | 0.907 |
V$NKXH | Homeodomain protein NKX3.2 (BAPX1, NKX3B, Bagpipe homolog) | 70 | 88 | 0.903 |
V$RBP2 | Jumonji, AT rich interactive domain 1B | 83 | 91 | 0.935 |
V$ZF35 | Human zinc finger protein ZNF35 | 92 | 104 | 0.922 |
V$WHNF | Winged helix protein, involved in hair keratinization and thymus epithelium differentiation | 98 | 108 | 0.941 |
1) Similar and/or functionally related transcription factor binding sites are grouped into so-called matrix families.
CpG sites | Breed | CD3− | CD3+ | CD3+ | CD4+/CD8+ | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
|
||||||||||
CD4−CD8− | CD4+CD8− | CD4−CD8+ | CD4+CD8+ | CD4−CD8− | CD4+CD8− | CD4−CD8+ | CD4+CD8+ | ||||
CpG_1 | L | 0.00 | −0.15 | 0.06 | 0.06 | −0.04 | 0.09 | −0.13 | −0.26* | −0.03 | 0.17 |
CpG_2 | DP+L | −0.05 | −0.29** | −0.27** | −0.06 | −0.02 | −0.10 | 0.36** | 0.46** | 0.21* | −0.28** |
DP | −0.09 | −0.33* | −0.14 | −0.07 | 0.13 | −0.03 | 0.04 | 0.17 | 0.17 | −0.04 | |
L | 0.01 | 0.11 | −0.15 | 0.28* | 0.17 | 0.05 | −0.17 | 0.06 | 0.08 | 0.18 | |
CpG_3 | DP+L | 0.07 | 0.18 | 0.03 | −0.12 | 0.00 | 0.03 | −0.12 | −0.2* | −0.08 | 0.09 |
DP | 0.21 | 0.19 | 0.01 | −0.40** | −0.03 | −0.01 | −0.15 | −0.31* | −0.20 | 0.18 | |
CpG_4 | DP+L | 0.07 | −0.08 | 0.04 | −0.17 | 0.01 | −0.09 | −0.02 | −0.10 | −0.08 | −0.04 |
L | 0.13 | −0.15 | 0.02 | −0.33* | −0.05 | −0.09 | −0.01 | −0.07 | −0.12 | −0.04 | |
CpG_5 | DP+L | −0.20* | −0.23* | 0.13 | 0.03 | 0.07 | 0.01 | 0.06 | 0.03 | 0.11 | −0.08 |
DP | −0.34* | −0.40** | 0.14 | 0.09 | 0.05 | −0.01 | 0.20 | 0.25 | 0.26 | −0.28* | |
L | −0.06 | −0.43** | 0 | −0.15 | 0.00 | −0.1 | 0.30* | 0.04 | 0.07 | −0.28* | |
CpG_7 | L | 0.00 | −0.27* | −0.08 | −0.01 | 0.09 | −0.15 | 0.23 | 0.12 | 0.06 | −0.24 |
CpG_8 | DP+L | 0.03 | −0.29** | 0.06 | 0.05 | −0.01 | −0.12 | 0.05 | 0.03 | −0.05 | −0.10 |
L | 0.04 | −0.32* | 0.14 | 0.09 | 0.01 | −0.15 | 0.02 | −0.05 | −0.10 | −0.08 |
1) The value in Table 3 above represented correlation coefficient between CpG sites methylation frequencies and T lymphocyte subpopulation traits.