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Anim Biosci > Accepted Articles
https://doi.org/10.5713/ab.24.0701    [Accepted] Published online February 27, 2025.
Effects of milk fortification with an advanced chelated trace minerals supplement on growth, health, and nutrient digestibility in dairy calves
Hossein Rajaei-Sharifabadi1,2,*  , Hadi Rahmani1  , Zahra Shokri1  , Saideh Fakharzadeh3  , Somayeh Kalanaky3  , Mohammad Hassan Nazaran3,*  , Ahmad Reza Seradj2,4 
1Malayer University, Malayer, Iran
2Universitat de Lleida, Lleida, Spain
3Department of Research and Development, Sodour Ahrar Shargh Co, Tehran, Iran
4Agrotecnio CERCA Center, Lleida, Spain
Correspondence:  Hossein Rajaei-Sharifabadi, Tel: +34 641852952, Fax: +34 973702000, Email: hrajaei@malayeru.ac.ir
Mohammad Hassan Nazaran,Email: mnazaran@nanochelatingtechnology.com
Received: 9 October 2024   • Revised: 6 January 2025   • Accepted: 4 February 2025
Abstract
Objective
Recent advancements in Chelate Compound technology offer improved bioavailability of trace minerals, potentially enhancing growth performance and reducing disease incidence. Milk fortification provides an efficient way to supplement young calves before they transition to solid feed. This study evaluated the response of dairy calves to milk fortification with an advanced chelated trace minerals supplement containing Zn, Mn, Cu, Fe, Co, Cr, and Se, each selected for their specific roles in calf development, synthesized using Chelate Compounds technology.
Methods
Forty-two Holstein dairy calves (21 male and 21 female) were randomly assigned to three experimental groups: control (CON, unfortified milk), chelated minerals (BON, milk fortified with chelated trace minerals), and inorganic minerals (IOR, milk fortified with inorganic trace minerals). Calves received their respective milk treatments daily from d 3 until weaning at 70 d of age. Growth performance and body measurements were measured throughout the experimental, while rectal temperature, fecal consistency, and frequency of medical treatment were recorded until d 21. Blood metabolites and nutrient digestibility were also determined.
Results
BON showed significant positive effects on body weight and some body measurements, with trends towards improved average daily gain and feed efficiency. The calves in BON group showed a lower fecal consistency index and lower frequency of medical treatments compared to CON and IOR. Lower globulin levels as well as higher levels of albumin and albumin/globulin ratio were observed in BON compared to the other two groups. The activities of liver enzymes were higher in IOR than BON and CON group.
Conclusion
These findings suggest that milk fortification with advanced chelated trace minerals have the potential to improve growth performance and health in dairy calves, while inorganic sources showed no benefits. Further research is needed to determine optimal supplementation levels and long-term effects on health and productivity of dairy calves.
Keywords: Advanced Chelate Compounds technology; Body measurements; Fecal consistency; Medical treatment; Organic trace minerals


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