In vitro Antioxidative Properties of Lactobacilli

Kim, H. S.; Chae, H. S.; Jeong, S. G.; Ham, J. S.; Im, S. K.; Ahn, C. N.; Lee, J. M.

doi:2006.19.2.262

Article

Animal Products

Asian-Australasian Journal of Animal Sciences 2006;19(2): 262-265.
https://doi.org/10.5713/ajas.2006.262 Published online December 7, 2005.

In vitro Antioxidative Properties of Lactobacilli

H. S. Kim, H. S. Chae, S. G. Jeong, J. S. Ham, S. K. Im, C. N. Ahn, J. M. Lee

Abstract

The antioxidative properties of lactobacilli originating from humans (Lactobacillus acidophilus KCTC 3111, Lactobacillus jonsonii KCTC 3141, Lactobacillus acidophilus KCTC 3151, and Lactobacillus brevis KCTC 3498) were investigated using in vitro methods, including inhibition of lipid peroxidation, resistance to hydrogen peroxide and hydroxyl radical, hydroxyl radical scavenging activity, and glutathione peroxidase (GPX) activity. L. acidophilus KCTC 3111 showed the highest inhibition of lipid peroxidation in both intact cells (49.7%) and cell lysate (65.2%). This strain exhibited resistance to hydrogen peroxide and hydroxyl radical, which was viable for 7 h in the concentration of 1.0 mM hydrogen peroxide. In addition, this strain showed high hydroxyl radical scavenging activity. In the GPX activity assay, the highest activity was measured in L. brevis 3498. GPX activity of L acidophilus 3111 was lower than that of L. brevis 3498.

Keywords: Lactobacillus; Lipid Peroxidation; Free Radicals