Association of a Single Nucleotide Polymorphism in the 5'-Flanking Region of Porcine HSP70.2 with Backfat Thickness in Duroc Breed

Chen, Ming-Yu; Huang, San-Yuan; Lin, En-Chung; Hseu, Tzong-Hsiung; Lee, Wen-Chuan

doi:2003.16.1.100

Article

Animal Breeding and Genetics

Asian-Australasian Journal of Animal Sciences 2003;16(1): 100-103.
https://doi.org/10.5713/ajas.2003.100 Published online January 1, 2003.

Association of a Single Nucleotide Polymorphism in the 5'-Flanking Region of Porcine HSP70.2 with Backfat Thickness in Duroc Breed

Ming-Yu Chen, San-Yuan Huang, En-Chung Lin, Tzong-Hsiung Hseu, Wen-Chuan Lee

Abstract

Higher environmental temperature affects the economic performance of pigs. Heat shock protein 70 has been shown to play an important role in thermoresistance. The purpose of this study was to assess the effect of a single nucleotide polymorphism in the 5''''-flanking region of porcine HSP70.2 on growth performance in Taiwanese Duroc. The genotype of this nt 393 polymorphic site could be verified by digestion with Bsa WI restriction enzyme of a PCR product. Pigs with TT and TC genotypes have thinner backfats than those with CC type (p<0.05). The result suggested that the polymorphic Bsa WI site in the 5''''-flanking region of porcine HSP70.2 may be used as a marker for the early selection of ultrasonic backfat thickness in Duroc pigs.

Keywords: Pigs; Duroc; Heat Shock Protein 70; Growth Performance; Polymorphism