Heterosis Effects of Body Weight and Jumping Height in Rotational Crossing of Two-Subspecies of Mice

Kurnianto, E.; Shinjo, A.; Suga, D.

doi:2000.13.7.888

Article

Animal Breeding and Genetics

Asian-Australasian Journal of Animal Sciences 2000;13(7): 888-893.
https://doi.org/10.5713/ajas.2000.888 Published online July 1, 2000.

Heterosis Effects of Body Weight and Jumping Height in Rotational Crossing of Two-Subspecies of Mice

E. Kurnianto, A. Shinjo, D. Suga

Abstract

The present study was conducted to evaluate heterosis effects of body weight and jumping height for successive generations of rotational crossing using two subspecies of mice which are very different in body weight and in genetic relationship from each other. Domesticated laboratory mouse CF#1 (C) and Yonakuni wild mouse (Y) were used as materials. Two groups of rotational crossing was made according to the parent used at the beginning of crosses, C male횞Y female and Y male횞C female. These crosses were done to produce the first (G1 and G1''''''''), second (G2 and G2'''''''') and third generations (G3 and G3'''''''') with sire used was alternated. Individual body weights were weighed at 1 (wk1), 3 (wk3), 6 (wk6) and 10 weeks of age (wk10) and jumping heights were measured at six weeks of age (wk6). Only the first litter used. For body weight, results of this study showed that genetic group effects were significant (p<0.01) source of variation at all ages studied. Sex effects were significant (p<0.01) at wk3, wk6 and wk10, but not at wk1. Significant interaction effects (p<0.01) between genetic group and sex were found at wk6 and wk10. The C mice with large maternal effects produced heavier offspring body weight and crosses using sire of this subspecies maintained heavy weight compared to wild Y mouse sire that has small body size. Heterosis tended to exist at the rotational crossing started from Y male C female. For jumping height, effects of genetic group and sex were significant, sire and dam effects (heterosis) exhibited from the first to third generations, and no maternal effects were observed.

Keywords: Rotational Crossing; Two-Subspecies of Mice; Body Weight; Jumping Height; Heterosis