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Review Paper
Asian-Australasian Journal of Animal Sciences 2000;13(3): 390-400.
DOI: https://doi.org/10.5713/ajas.2000.390    Published online January 1, 2000.
Luteal Prostaglandin F2α: New Concepts of Prostaglandin F2α Secretion and Its Actions within the Bovine Corpus Luteum - Review -
K. Okuda, D. J. Skarzynski
The corpus luteum (CL) is a temporary endocrine gland whose main function is to secrete progesterone to support pregnancy. On the other hand, the cyclic bovine CL has also been shown to be a site of prostaglandin F2慣 (PGF2慣) production. Although there is general agreement that endometrial PGF2慣 is an essential luteolysin in cattle, luteal PGF2慣 seems to play a luteotropic role as an autocrine and/or paracrine factor, especially for the development and maintenance of the CL. This supposition is based on evidence that some of the prerequisites for autocrine/paracrine mechanisms are present, including local production of PGF2慣 and the existence of specific binding sites within the CL. The purpose of this paper is to review the regulation of luteal PGF2慣 secretion, its action on CL as an autocrine and/or paracrine factor and the receptivity of bovine CL to PGF2慣.
Keywords: PGF2慣 Receptor; PGF2慣; Corpus Luteum; Luteolysis; Cow
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