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Development and Characterization of a Novel Anti-idiotypic Monoclonal Antibody to Growth Hormone, Which Can Mimic Physiological Functions of Growth Hormone in Primary Porcine Hepatocytes |
Hai-Nan Lan, Hai-Long Jiang, Wei Li, Tian-Cheng Wu, Pan Hong, Yu Meng Li, Hui Zhang, Huan-Zhong Cui, Xin Zheng |
Anim Biosci. 2015;28(4):573-583. Published online February 4, 2015 DOI: https://doi.org/10.5713/ajas.14.0600 |
OR11,4 A monoclonal antibody that targets a novel site on the beta3 subunit of the alphaVbeta3 integrin blocks lesion development in a porcine model of diabetes accelerated atherosclerosis Growth hormone-specific induction of the nuclear localization of porcine growth hormone receptor in porcine hepatocytes OR12,72 Explore the mechanism of growth hormone signaling with growth hormone receptor monoclonal antibodies Promotion of animal growth with a monoclonal anti-idiotype specific to anti-porcine growth hormone antibody Effects of growth hormone therapy on cardiac and respiratory functions in growth hormone-deficient adults Physiological regulators of growth hormone secretion The phospholipase C-InsP3 pathway is involved in calcium mobilization induced by growth hormone in hepatocytes P-10 REGULATION OF GROWTH HORMONE-INDUCED [CA2+]C OSCILLATIONS IN RAT HEPATOCYTES BY PANCREATIC HORMONES P102 Growth hormone-induced oscillations in cytosolic free Ca2+ in single rat hepatocytes, modulation by different agonists Dexamethasone inhibits both growth hormone (GH)-induction of insulin-like growth factor-I (IGF-I) mRNA and GH receptor (GHR) mRNA levels in rat primary cultured hepatocytes |