Association among Egg Productivity, Granulosa Layer IGF-I, and Ovarian IGF-I in Korean Native Ogol Chicken

Kang, W. J.; Seo, D. S.; Ko, Y.

doi:2003.16.3.325

Article

Animal Breeding and Genetics

Asian-Australasian Journal of Animal Sciences 2003;16(3): 325-330.
https://doi.org/10.5713/ajas.2003.325 Published online January 1, 2003.

Association among Egg Productivity, Granulosa Layer IGF-I, and Ovarian IGF-I in Korean Native Ogol Chicken

W. J. Kang, D. S. Seo, Y. Ko

Abstract

There exists considerable evidence that insulin-like growth factor-I (IGF-I) is involved in the regulation of ovulation rate and follicle development. IGF-I is believed to modulate the effects of gonadotropins on follicular growth and cell differentiation via paracrine and autocrine mechanisms. Therefore, this study was performed to relate the expression of IGF-I on ovaries and follicles with egg productivity at 60 wk. The egg productivity of 70 KNOC was recorded from 20 to 60 wk. Blood was taken every 10 wk and ovaries and follicles were taken at 60 wk. Serum IGF-I and IGF-I of ovaries and follicles were measured by radioimmunoassay. Based on egg production levels up to 60 wk and ovarian IGF-I expression at 60 wk, respectively. Chickens were divided into two groups, high and low. Egg production and serum IGF-I in the high IGF-I group were higher than those in the low group. Moreover, the IGF-I expression of follicles in the high ovarian IGF-I expression group was higher than that in the low group. These finding are consistent with the report that IGF-I indirectly regulates ovulation in chickens, suggesting that this regulation may play an important role in improved egg productivity.

Keywords: IGF-I; Egg productivity; Ovary; Follicle; KNOC