Insulin responsiveness to glucose and tissue responsiveness to insulin in cows, sheep and pigs

Sano, H.; Terashima, Y.

doi:1991.4.1.41

Article

Animal Reproduction and Physiology

Asian-Australasian Journal of Animal Sciences 1991;4(1): 41-45.
https://doi.org/10.5713/ajas.1991.41 Published online March 1, 1991.

Insulin responsiveness to glucose and tissue responsiveness to insulin in cows, sheep and pigs

H. Sano, Y. Terashima

Abstract

Insulin responsiveness to glucose and tissue responsiveness to insulin, using the hyperglycemic clamp and the hyperinsulinemic euglycemic clamp techniques, were compared among cows, sheep and pigs. The plasma insulin concentrations during the hyperglaycemic clamp period were highest (p<0.05) in cows, followed by sheep and pigs. The glucose infusion rate in the hyperinsulinemic euglycemic clamp technique was greater (p<0.01) in pigs than in cows and sheep. These results suggest responsiveness to insulin is higher in pigs than in cows and sheep.

Keywords: Insulin; Glucose Clamp; Cow; Sheep; Pig